Expansion On The Recent Discoveries Concerning Nitric Oxide :: essays research papers

Expansion on the Recent Discoveries Concerning Nitric Oxide as presented by Dr. Jack R. Lancaster   Ã‚  Ã‚  Ã‚  Ã‚  Nitric Oxide, or NO, its chemical representation, was until recently not considered to be of any benefit to the life processes of animals, much less human beings. However, studies have proven that this simple compound had an abundance of uses in the body, ranging from the nervous system to the reproductive system. Its many uses are still being explored, and it is hoped that it can play an active role in the cures for certain types of cancers and tumors that form in the brain and other parts of the body.   Ã‚  Ã‚  Ã‚  Ã‚  Nitric Oxide is not to be confused with nitrous oxide, the latter of which is commonly known as laughing gas. Nitric oxide has one more electron than the anesthetic. NO is not soluble in water. It is a clear gas. When NO is exposed to air, it mixes with oxygen, yielding nitrogen IV dioxide, a brown gas which is soluble in water. These are just a few of the chemical properties of nitric oxide. With the total life expectancy of nitric oxide being from six to ten seconds, it is not surprising that it has not been until recently that it was discovered in the body. The compound is quickly converted into nitrates and nitrites by oxygen and water. Yet even its short-lived life, it has found many functions within the body. Nitric oxide enables white blood cells to kill tumor cells and bacteria, and it allows neurotransmitters to dilate blood vessels. It also serves as a messenger for neurons, like a neurotransmitter. The compound is also accountable for penile erections. Further experiments may lead to its use in memory research and for the treatment of certain neurodegenerative disorders. One of the most exciting discoveries of nitric oxide involves its function in the brain. It was first discovered that nitric oxide played a role in the nervous system in 1982. Small amounts of it prove useful in the opening of calcium ion channels (with glutamate, an excitatory neurotransmitter) sending a strong excitatory impulse. However, in larger amounts, its effects are quite harmful. The channels are forced to fire more rapidly, which can kill the cells. This is the cause of most strokes. To find where nitric oxide is found in the brain, scientists used a purification method from a tissue sample of the brain. One scientist discovered that the synthesis of nitric oxide required the presence of calcium, which often acts by binding to a ubiquitous cofactor called calmodulin. A small amount of calmodulin is added to the enzyme preparations,

Genie †The Wild Child Essay

Genie was discovered at the age of thirteen living completely isolated in a room in her parent’s house, with nothing to look at, restrained to a potty chair for most of her life. At this time, Genie was still wearing a diaper, did not have the ability to communicate and could barely walk. Her father’s reason for keeping Genie isolated was that he believed that she was retarded from birth. Her mother takes no responsibility, claiming she too was abused by her controlling husband. Both of her parents were charged with child abuse; but her father killed himself shortly after and her mother was able to beat the charges. Genie was taken to The Children’s Hospital of Los Angeles where she would meet several specialist assigned to her case. Shirley, an isolation specialist, stated that Genie was the most extreme case of isolation that he had encountered. Specialist started to run test to diagnose the extent of Genie’s deficiencies. Genie had a strange bunny walk, spat and clawed. It was believed that she was beat for making noise, so she remained silent. Was she born brain dead or did she become mentally challenged? First they conducted a test to monitor the electric activity in her brain. This four night study showed that Genie had a high number of sleep spindles, which shows abnormal brain wave patterns. By that spring, Genie had learned a hundred words and was beginning to speak verbally; which allowed her to express herself. Signs of her mental and physical growth were striving. She explored things using her lips and face. Doctors showed confidence in her success. Genie moved in with her Special Education teacher, Mrs. Butler. This was Genie’s first run in a foster home. Notes were taken on Genie’s obsession with hoarding objects, especially containers of liquid. This has also been recorded in other cases of isolated children. Mrs. Butler took it upon herself to cut off all contact with the other members of Genie’s case and filed a request to gain permanent custody, which was rejected by Social Services and Genie returned to Children’s Hospital for a short period of time. Genie was then placed with Mr. Riddler, who took on many of the roles in the case. Mrs. Riddler worked with Genie and taught her how to express her rage through fits, instead of physically hitting herself. She soon learned to verbally communicate her degree of unhappiness. Mrs. Riddle also helped Genie to verbalize memories from her past. Genie was able to use words and her vocabulary continued to grow. She started going to a nursery school and learned sign language. Case members still disagreed on Genie’s prognoses. Some believed that Genie was still brain dead from birth due to abnormal brain activity; while others believed that she had mental delays due to isolation, showing that her mental age was increasing. With all of Genie’s verbal achievements, she was not able to make grammatical sentences. In 1975 the research case on Genie ended and she returned to her mother’s care. Soon her mother realized that Genie was too much for her to handle and she was moved from foster family to foster family. Genie faced abuse and harassment during this time. In one situation, Genie was punished for vomiting, resulting in Genie refusing to open her mouth; ultimately, regressing Genie’s progress. Genie’s case strongly sides with the nurture debate. Emphasis is placed on Genie’s ability to overcome her early environment by allowing her to experience the world and to gain personal relationships. Genie’s ability to learn to verbalize after puberty shows that human development can occur and does not need to be learned during infancy. By Genie gaining personal relationships, she was able to learn how to express her emotions (happy, sad, angry). This proves that her environment is an important factor in her development. This study seems to be most consistent with Skinner’s Behavior Theory. Skinner believed that a person’s development was caused by the consequences of their behavior. An example would be when Genie was encouraged to speak and socialize, she did and enjoyed it. When Genie was punished for vomiting, she felt that opening her mouth was bad and stopped. Skinner also believed that the nurture side of the debate was important, development depends on experiences and people are shaped by their environment. All of which seem to be a theme in Genie’s case.

Individual Analysis

Individual Case Analysis Contents 1. 0Analysis Using Motivation Theories1 1. 1Equity Theory1 1. 2Expectancy Theory1 1. 3 Three-need Theory†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 2 2. 0Criticisms of the Management Functions3 3. 0Main Problems Defined4 4. 0References5 5. 0Appendices6 5. 1Appendix 1: SWOT Analysis6 5. 2 Appendix 2: Equity Theory Table†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 7 1. 0Analysis Using Motivation Theories 1. 1Equity Theory According to Robbins, Bergman, Stagg and Coulter (2003) equity theory was developed by J. Stacey Adam. Campebell, Dunnette and Miller (1969) states the purpose of this theory is aim at employees’ assimilation from a job situation. Kaplan, Reckers and Reynolds (1986) notes these are outcomes, in relation to the efforts they put in, inputs, and then compare with others. In the case, Lisa compares her input-outcome ratio with Leanne, which seems imbalance and unfair. Lisa feels jealous as Steve decided to go again her suggestion to hand over half of her workload to the youngest team member, Leanne. She also sees that Leanne became more dominant. Lisa was treated unfairly by two other members putting the blames at her who forced Steve to reprimand her. The distraught Lisa’s thinking was to give other members of the team who has more experience to take over some of her work rather than Leanne. In the end Lisa lodged a compensation claim for her nervous breakdown cased by Leanne. Also stated by Robbins, Bergman, Stagg and Coulter (2003), employees’ motivation is influenced by rewards. Base on the above-mentioned, Steve should use the equity method in treatments of staff. Therefore, whenever an employee assess their own equity and perceive inequity, he or she will act to correct the situation rather than lack of motivation. Please refer to 5. 2 Appendix 2 for table showing equity theory. 2. Expectancy Theory According to Montana and Charnov (2000), expectancy theory shows that rewards could motivate employees to increase their efforts. Taylor (1964) notes this encourages better performance leading to a positive outcome. Steve applied the expectancy theory under his management. By doing this, he made an announcement that he will increase employees’ salary base on performance rating. Due to massive increase in training loads, Lisa was overworked and with projects behind schedule. Then Green (1992) states on of the believing is that employees believe if they perform well, they will get the reward. Leanne is an ambitious person that is why she offers help as she believes in good performance could get better outcome and reward. On the other hand, according to Montana and Charnov (2000), an employee can decide on which outcome they prefer. Due to immense pressure from overload and conflict with Leanne, Lisa has made a decision to take stress leave. This reduces the efforts Lisa requires to put into her work. 3. Three-need Theory McClelland (as quoted by anonymous, 2008) states an employee’s motivation and effectiveness are influenced by the following: Need for Achievement – McClelland (quoted by Pattanyak, 2006) notes motivation that influences employees to direct his or her behaviour towards attaining goals. According to the achievement explained, Lisa is not motivated to challenge of orking at a problem and do not accept any personal responsibilities for failure, rather leaving the actions and chance for Leanne to achieve the outcome. Need for Affiliation – Courtney (2002) notes McClelland had suggested that people are motivated by different things. Also, base on the statement stated by Tosi, Mero and Rizzo (2000), McClelland’s theory on affiliation has a need for friendly relationships an d have good interactions with others. These people can co-operate well in a team. Referring to the explanation of affiliation, Lisa’s jealousy and conflict with Leanne had caused friction and resignation in the team. It shows there is a lack of communication skills and co-operate for Lisa in the team. Lisa’s personal attitude problem towards Leanne also caused her relationship problems with colleague and manager. Need for Power – McClelland (quoted by Pattanyak, 2006) notes that people at a high position would want the power to control other people for their own goals. According to Ved (2005) there are: Social – controls the company’s movement, and Personal – influence others to further the desire. Leanne entered InsureCo. as a new team member under Lisa’s leadership in a team. Soon after, Leanne quickly made good relationship with the manager and quick to promote her skills, which lead her over stepped the power of Lisa. Therefore, Lisa felt she was unable to control Leanne to achieve her outcome. Lisa has also lost control of her team when couple of the team members resigned. With the lost control of power, Lisa lost the battle to be promoted. Therefore, she is not motivated. 2. 0Criticisms of the Management Functions The management of InsureCo. has several negative practices, they are: – The way Steve manages the company’s environment The way Steve supervise employees, and – How staff co-operate with each other as a team. According to Bell and Smith (2006), the use of communication and verbal skills for managers is vital in their management work. By listening to employees, companies could improve employees’ job satisfaction. According to Deci and Ryab (1985), the greatest motivation act is managers could do for his or her empl oyee is listening. In this case, Steve does not communicate effectively to his staff about his expectations and resolving problem issues within the working environment. He does not think of the concern that if he recognise the new employee, Leanne, Lisa would complain about the recognition. To prevent the complaining obstacle, Steve should listen to Lisa when she complained about Leanne in regards to her I. T. skills. Steve should act on the complaint and assess Leanne’s ability in the I. T. field. If it does prove that she has the skills, there would not be jealousy in Lisa. Schuler and Jackson (1999) mentioned that fair treatment of employee which will make them more committed in an organisation. It means, Steve should treat Lisa and Leanne equally. It is not where he should reprimand Lisa in front of her colleagues and in a way without her giving reasons. This is an embarrassment for Lisa. This also shows there is a lack of fair treatment within the management system of the company. According to Cook (1999), employees will produce more effort in their work when they are appreciated, valued and understood by the employer. Steve should set up a guide of basic principles to coach employees when there is a problem. Base on the value of Lisa to the company, Steve should not reprimand her straight away without any options for explanation and when he did reprimanded her he should explain his decision. Steve could improve the relationship between Lisa and Leanne by informing them how others feel, how much effect can cause, and suggest them how to improve themselves. Steve’s management at InsureCo. he is committed to the company’s goals, according to Salaman (2001), it sometimes refers to as mission statement. In the case, increase salary was any approach that Steve regarded as important. The aim is to fend off growing competition. The increase of salary could not always motivate his staff. The reasons are mentioned in the previous citations. 3. 0Main Problems Defined |Primary Problems |Secondary Problems | |Poor leadership – New leadership of the firm, lack of managerial |Poor motivational skills | |experience. |Staff lacks motivation | |Poor planning – No technical training system been put in. No specific job description written for employees | |No formal policies written for rewards and punishment |Increase in workloads | | |Lack of co-operation | | |Manager has poor communication skills | | |Ineffective communication of expectations | | |Employees’ value not appreciated | | |Overload work causes delays | | |Multitask been given to employees | | |Management has no understanding of employees’ needs | | |Poor relationship between staff and manager | | |Pressure in the training department | | |Lack of fair treatment for staff | 5 . Appendices 5. 1Appendix 1: SWOT Analysis [pic] 2. Appendix 2: Equity Theory Table by Robbins, Bergman, Stagg and Coulter (2003) Perceived ratio comparisonEmployee’s assessment Outcomes AOutcomes B Inputs A Inputs B (Inequity-over rewarded) ———————– Threats ? Exposed weaknesses in the company ? Strong global competitors ? Complaints from staff ? Compensation claim from staff Opportunities ? Government proposed new Financial Services Reform Bill – Make sure entire staff had been trained Weaknesses ? Poor leadership ? Poor planning ? No formal policies for rewards & punishments are written ? Poor motivational skill ? Staff lacks motivation ? No specific job description written for employees ? Increase of workload ? Lack of co-operation ? Poor communication skills ? Staff’s value not appreciated ? Overload work causes delays ? Multitask given ? Management has no understanding of employees’ needs ? Poor decision making ? Pressure in the training department ? Lack of fair treatment for employees ? Strengths ? Large finance and insurance company ? Market presence ? Large customer base ? Long profitable history ? Promotions for employees ?

Luxury Fashion Brand Essay

To be successful in India, it is both necessary to gauge the financial potential as well as the mindset of the Indian luxury consumer. This will help in bringing forth the right product offerings to the Indian consumer as well as targeting them better. There are conventional foundations for ensuring success of a brand and they are listed below in brief: * The brand must be â€Å"expansive† – Which means it should be full of innovation opportunities for the marketer and in terms of satisfying the different needs of the luxury consumer. * The brand must tell a story – One of the best ways for an organization to compete and distinguish yourself from the rest of the pack is to tell your brand story. The story should be so powerful that it should make customer act as the way you want. * The brand must be relevant to the consumers’ needs – Depending upon the mindset of the luxury class, it is necessary for a brand to satisfy those needs, whether they be for recognition or functional use etc. * The brand must align with consumers’ values – A brand that does not concur with the basic values of a consumer’s society has a small chance of succeeding because luxury items are identification for a luxury consumer. This makes it difficult for the consumer to adopt the brand in such cases. * The brand must perform – Irrespective of which category the brand belongs to, a performance assurance is a must for the brand. Based on the inputs given above as well as an understanding of the decision making process of the luxury consumer, we recommend the following paths for luxury marketers based on what Indian consumers really desire from their luxury brands, i. e. product brand, dealer/store brand and price/value relationship : (The price / value relationship has been accorded less focus since the Indian Consumer is at a phase when cost of luxury is secondary to its appeal / benefits) 1. Brand Me Affluent! – It is essential for marketers to ensure that the recognition value of their brands is always high so that it lends a sense of affluence to the consumer, which can only come if others around him / her perceive the brand to be a top-notch luxury brand. This can come from either being aligned with the most successful celebrities or being a part of elite events and promotions. 2. Nothing but the Best – This is a golden opportunity for the marketer to earn greater margins by adding customized value to his line of luxury goods. These added-value customized goods will ensure that the customer feels he has something more than just the ordinary range of luxury goods available. 3. Luxury is having the world at my fingertips – First! – A luxury marketer will not only have to be faster than his competitors in reaching out to the consumer, to gain a share of wallet but also continuously offer innovative products that serve to differentiate between the consumers. 4. â€Å"Ethnic Chic† – The Fusion of Local & Global goods – This point is connected to the strategy of a product being in line with the consumers’ values for it to be adopted. Apart from this, in the Indian context, ethnicity is also a fashion statement in many product categories. 5. You Think I’m Demanding? Next! – The marketer’s job should be a constant endeavor to offer newer luxury goods to the consumer, in sync with their needs. In addition to that, marketers will need to make sure that each and every single consumer has to be treated with a high-level of personalized attention, given the nature of the product and the consumer. Even minor Shortfalls in this case will have the consumer shifting their brand preferences to those marketers who can satisfy their needs better. 6. CANNIBALIZATION OF BRANDS – It thus becomes essential to ensure that successful celebrities are partnered with at the right time, thereby both eliminating chances of Competition as well as delivering the right aspirational / appeal message to the intended audience. Conclusion The starting point for identifying successful luxury brand strategies in India has been established by identifying certain salient aspects of luxury brands that remain constant as well as identifying the stage of mindset of the Indian consumer towards these brands. The focus is now towards ‘how soon’ luxury brands will enter the market to gain a first mover advantage, which is of significant importance in India. Apart from how soon, we primarily focus on ‘how will’ luxury brands cater to the mainly aspirational needs of the Indian consumer. A word of caution that goes for luxury marketers, irrespective of their brands and Geographical presence – The luxury consumer is always looking for newer ways to Satisfy his continuously changing needs. Hence, the need to keep a close tab through insightful research is of prime importance. As far as India is concerned, given the rapidly accelerating affluence of the Masses, the scenario is set to witness a boom. The ones who will be riding the Wave will be the ones who’ve kept their ears open to each and every word of their Each and every customer. After all, in the luxury business, no marketer can afford the luxury of treating its consumers as a loosely bunched segment.

TermPaper2types of promotional strategies Term Paper

TermPaper2types of promotional strategies - Term Paper Example There are four types of promotional strategies, which are: online promotion, traditional media, push marketing and pull marketing. Online Promotion is also called online marketing or Emarketing. It represents advertising the products through the internet. Online promotion gained great popularity as almost every company tries to create its own website to attract customers online. Now almost all the people use internet to buy different products as online they can have more opportunities. The main disadvantage of online promotion is changes which happen rapidly. In order to have successful online promotion, every company needs to have efficient online promotion strategy. The most important characteristic feature for modern managers is insight. It is essential to have good education and be aware of the situation (Kotler). Online promotion is the field that changes rapidly, thus it is very important to be always on time with the advertising and have the appropriate approach. (Orton, 2009). The most popular and beneficial form of online promotion is pay-per-click advertising, when the advertiser pays for the promotion only after the ad is clicked. This kind of advertising is very demanding as it does not accept all the businesses. Some companies can’t advertise their products with the most popular advertising engines as they have many restrictions and special rules for companies. Those companies, which use pay-per-click approach, have many benefits. They have a perfect opportunity to attract customers without paying much for the advertising. Thus, online promotion represents the cheapest way to advertise products and services Any advertising campaign uses many traditional media channels such as television, radio, newspapers, etc. An advertising campaign can be defined as a number of different kinds of advertising, which have the common purpose and content. Ad campaign is the essential part of management strategy. Management strategy implies

Paulson Statement on Regulation Essay Example | Topics and Well Written Essays - 1000 words

Paulson Statement on Regulation - Essay Example He reiterated his confidence in the strength and resiliency of the country's capital markets, and that the country would be able to work its way out of the situation. In his introduction, the Secretary remarked that the most pertinent priority of the government was to limit the actual effects of this crisis on the country's real economy. He advised that the key to keeping the country's economic state above water was to maintain liquid and stable financial markets, and that banks must put in their fair share by making credit readily available both to ordinary citizens and businesses. He added that there must be vigilant efforts introduced in order to dilute the destructive effects of the recent housing downturn on the economy. In addressing the importance of orderly financial markets, Paulson stated that the recent turmoil the capital markets have been facing were largely in part to the reduced access to short-term funding, which in turn caused widespread liquidity issues even with the biggest investment banks. As a result of these volatile conditions, Bear Sterns, the country's 5th largest investment house, found itself in bankruptcy. He justified the Federal Reserve's intervention leading to the JP Morgan buyout, stating that market stability was the primary concern of the government and the issue warranted prompt resolution. In light of the Bear Sterns fiasco, the Federal Reserve took a leap of faith by putting forth a temporary program which is meant to provide short-term liquidity to primary dealers. From a historical perspective, such bold moves by the country's central lending institution had not been propagated since the 1930's. While Paulson praised the Federal Reserve for its creativity in dealing with a potentially crippling situation, he chided that such drastic measures also have corresponding repercussions which need to be addressed. He argues that while commercials banks have traditionally had access to the Federal Reserve's liquidity facilities, these have been accompanied by strong regulation and supervision to avoid and potential pitfalls. Hence, the same measures should be enacted this time around if only for the sake of prudence. Paulson suggests that in opening the discount window temporarily to non-insured and non-depository institutions, tighter measures must be enacted in screening these institutions, which will enable them to make better informed lending decisions. In explaining the current mortgage crisis, he admits that its rapid free-fall has adversely affected both financial institutions and capital markets alike. Far from putting the blame on the inherently flawed sub-prime mortgage system, he argues that unsustainable home price appreciation in certain key areas was the primary driver behind the crisis. Also, once stability is restored to the housing sector, this will lead to a much more favorable situation for institutions involved with mortgage-backed securities. Paulson admits that with the current housing crisis, the availability of mortgage financing has been almost non-existent, due largely in part to the crippling liquidity problems that have beset lending institutions. He offers that in order for the housing and mortgage industry to get back on its feet, government-backed institutions such as Fanny Mae and Freddie Mac should be willing to

Leaders in Today's Organizations Research Paper Example | Topics and Well Written Essays - 750 words

Leaders in Today's Organizations - Research Paper Example A research study shows that there are different factors which are necessary for being an emotionally intelligent person. The leaders who are self-aware of their personalities and can understand their strengths and weaknesses can be emotionally intelligent because they can also deal with the emotions of other people (Downy, 2011). Another important characteristic is self-regulation which is required for developing emotional intelligence. A self-regulation means the maturity level of the person. A person should be mature enough to handle the criticism and all other matters, only then he can be termed as an emotionally stable and intelligent person. An emotionally intelligent leader should have excellent communication skills so that he can control and manage people and their emotions (Downy, 2011). Conflict resolution and social awareness are two different factors, which make for being an emotionally stable and intelligent leader. Currently, there are many multinational firms, which are focusing on the emotional intelligence of their managers so that they can prove themselves as effective leaders. The concept of accountability is an important factor from the leadership point of view. If a leader feels he owns accountability towards his responsibilities then it means that he is taking care of his own duties and rights. On the other hand, if a leader develops a sense of accountability for his followers then it means that he is creating an environment where everyone is responsible and answerable for his duties and actions (Gentry, 2007). In both situations, the ultimate benefit will go for the leader and the organization because if the followers feel the responsibility then it means that they will accurately follow the instructions of the leader.